1 Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor 45363,
2 Department of Biology, Faculty of Mathematics and Natural Sciences, Padjadjaran University,
Jatinangor 45363, Sumedang, Indonesia;
3 Division of Applied Life Sciences, Graduate School of Life and
Environmental Sciences, Osaka Prefecture University, Gakuen-cho, Sakai, Osaka 599-8531, Japan
Flavonoids compounds such as kaempferol (1), kaempferol-3-O-β-D-glucopyranoside or astragalin (2) and
kaempferol-3-O-α-L-rhamnoside or afzelin (3) have been isolated from the fresh leaves of Kalanchoe tomentosa
(Crassulaceae). The chemical structure of isolated compounds 1-3 were identified by spectroscopic evidences and
comparison with those compound previously reported. Compounds 1-3 showed cytotoxic activity against P-388 murine
leukimia cells with IC50 values of 51.8, > 100 and 3.32 µg/mL, respectively.
This is an open access article licensed under the terms of the (https://creativecommons.org/licenses/by/4.0/legalcode), which permits unrestricted, noncommercial
use, distribution and reproduction in any medium, provided the work is properly cited.
* Address correspondence to this author at the Department of Chemistry,
Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jl.
Raya Bandung-Sumedang Km 21, Jatinangor 45363, Sumedang, West Java, Indonesia;
Tel/Fax: +62-22-7794391; E-mail: email@example.com