Effect of Adding Dexmedetomidine to Bupivacaine in Ultrasound Guided Rectus Sheath Block: A Randomized Controlled Double-blinded Study

Salem, Wafaa T; Alsamahy, Khaled A; Ibrahim, Wael A; Alsaed, Abear S; Salaheldin, Mohamed M

Effect of Adding Dexmedetomidine to Bupivacaine in Ultrasound Guided Rectus Sheath Block: A Randomized Controlled Double-blinded Study

Wafaa T Salem¹, Khaled A Alsamahy¹, Wael A Ibrahim¹, Abear S Alsaed², Mohamed M Salaheldin^{1, *}

¹ Department of Anesthesia and Pain Management, National Cancer Institute, Cairo University, Cairo, Egypt

² Department of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt

Article Information

Identifiers and Pagination:

Year: 2019
Volume: 13
First Page: 25
Last Page: 30
Publisher ID: TOATJ-13-25
DOI: 10.2174/2589645801913010025

Article History:

Received Date: 31/01/2019
Revision Received Date: 21/03/2019
Acceptance Date: 2/04/2019
Electronic publication date: 30/04/2019
Collection year: 2019

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© 2019 Salem et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

^* Address correspondence to this author at Department of Anesthesia and Pain Management, National Cancer Institute, Cairo University, Egypt Fom EL Khaleeg, Cairo, Egypt; Tel: +20237604220; Email: mail@mcs-center.com

Background:

Extended midline laparotomy incision is accompanied by intense pain postoperatively which affects patients’ physiology; therefore, good control of postoperative pain is mandatory to decrease the adverse effects on the body. Ultrasound-guided Bilateral Rectus Sheath Block (BRSB) is one of the options to achieve this goal.

Objective:

The study aimed to assess the analgesic potency of adding dexmedetomidine to bupivacaine in ultrasound-guided BRSB in cancer patients with a midline laparotomy incision.

Methods:

Sixty adult cancer patients planned for laparotomies with extended midline incision were included. Ultrasound-guided BRSB was performed immediately after the induction of anesthesia.

Patients were classified randomly into two groups; B group, where only bupivacaine was used for BRSB and BD group in whom a mixture of bupivacaine and dexmedetomidine was used.

Results:

A significant decrease in visual analogue scale scores, total morphine consumption, postoperative nausea and vomiting and postoperative cortisol levels was observed in group BD.

Conclusion:

Dexmedetomidine as an adjuvant to bupivacaine in US-guided rectus sheath block bilaterally proved to be effective for proper pain management postoperatively in cancer patients after extended midline abdominal incision.

Keywords: Rectus sheath block, Dexmedetomidine, Pain, Regional anesthesia, Midline abdominal incision, Abdominal cancers.

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RESEARCH ARTICLE

Effect of Adding Dexmedetomidine to Bupivacaine in Ultrasound Guided Rectus Sheath Block: A Randomized Controlled Double-blinded Study

Article Information

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Abstract

Background:

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Conclusion:

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