Acute Angioedema in a Patient on Long-term Angiotensin Converting Enzyme Inhibitor Following Oral Surgery: A Case Report

Awoniyi, Caleb A.; Yannaras, Steven; Bauerfeind, Julia M.

Acute Angioedema in a Patient on Long-term Angiotensin Converting Enzyme Inhibitor Following Oral Surgery: A Case Report

Caleb A. Awoniyi^{*, 1, 2}, Steven Yannaras², Julia M. Bauerfeind^{1, 2}

¹ North Florida/South Georgia Veterans Health System, Anesthesia Service, Gainesville, Florida, USA

² Department of Anesthesiology, University of Florida, Gainesville, Florida, USA

Article Information

Identifiers and Pagination:

Year: 2013
Volume: 7
First Page: 49
Last Page: 51
Publisher ID: TOATJ-7-49
DOI: 10.2174/1874321801307010049

Article History:

Received Date: 29/08/2013
Revision Received Date: 26/09/2013
Acceptance Date: 30/09/2013
Electronic publication date: 27/12/2013
Collection year: 2013

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© 2013 Awoniyi et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

^* Address correspondence to this author at the North Florida/South Georgia Veterans Health System, Anesthesia Service, Gainesville, Florida, USA; Tel: 352-374-6051; Fax: 352-379-7489; Email: Caleb.awoniyi@va.gov

A relatively common side effect of angiotensin converting enzyme inhibitors (ACE-I), used for the treatment of high blood pressure, is angioedema. Whereas, angioedema due to ACE-I usually appear during the first few days or weeks of treatment, delayed onset, years after initiation of treatment is often unrecognized and can lead to life-threatening adverse events. We present a case report of rapidly progressive tongue swelling a few hours following oral surgery in a 62-year-old male who had been on ACE-I therapy for seven years. Prompt recognition and treatment prevented an impending respiratory compromise that could have been catastrophic.

Keywords: Angiotensin converting enzyme inhibitor, angioedema, late-onset of angioedema, tongue swelling, hereditary angioedema, nasal intubation.

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RESEARCH ARTICLE

Acute Angioedema in a Patient on Long-term Angiotensin Converting Enzyme Inhibitor Following Oral Surgery: A Case Report

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