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The Open Bioactive Compounds Journal
(Discontinued)
ISSN: 1874-8473 ― Volume 9, 2020
Evaluation of Antioxidant Potential of Stem and Leaf Extracts of Himalayan Tinospora cordifolia Hook.f. & Thomson
Geetanjali Upadhyay1, Lalit M. Tewari1, Geeta Tewari2, *, Neha Chopra1, Naveen C. Pandey1, Santosh K. Upadhyay3, Rekha Gahtori3
Abstract
Background:
Medicinal plants are considered a rich source of ingredients, which can be used in drug development and synthesis. Tinospora cordifolia (Wild.) Hook.f. & Thomson, commonly known as guduchi, heart-leaved moonseed and giloya is a herbaceous vine of the family Menispermaceae, has several beneficial properties including antioxidant activity.
Aim:
The present study was carried out to analyze the antioxidant activity of leaf and stem extracts of Tinospora cordifolia by using DPPH (1,1-Diphenyl-2-picrylhydrazyl) and ABTS (2,2´-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)) free radical scavenging assays.
Materials and Methods:
Dried and powdered leaves and stem of T. cordifolia were extracted with methanol. Ascorbic acid was taken as standard. Total phenolic content was estimated by using Folin-ciocalteu's reagent while total flavonoid content by aluminium chloride reagent to find the correlation of polyphenols with antioxidant activity. ABTS assay of methanolic leaf and stem extracts showed the highest scavenging activity as compared to the DPPH assay.
Results:
Methanolic stem extract showed higher phenolic and flavonoid content along with antioxidant activity as compared to the methanolic leaf extract.
Conclusion:
The stem extract exhibited more antioxidant activity than the leaf extract with regards to the all parameters analyzed.
Article Information
Identifiers and Pagination:
Year: 2021Volume: 9
Issue: Suppl-1, M2
First Page: 2
Last Page: 8
Publisher Id: TOBCJ-9-2
DOI: 10.2174/1874847302109010002
Article History:
Received Date: 19/3/2020Revision Received Date: 19/4/2020
Acceptance Date: 11/5/2020
Electronic publication date: 18/06/2021
Collection year: 2021
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
* Address correspondence to this author at the Department of Chemistry, D. S. B. Campus, Kumaun University, Nainital, Uttarakhand, India; Tel: +09412438823; E-mail: geeta_k@rediffmail.com
| Open Peer Review Details | |||
|---|---|---|---|
| Manuscript submitted on 19-3-2020 |
Original Manuscript | Evaluation of Antioxidant Potential of Stem and Leaf Extracts of Himalayan Tinospora cordifolia Hook.f. & Thomson | |