REVIEW ARTICLE


Bone Marrow Transplantation



K. Ananda Krishna, K.R.S. Sambasiva Rao*
Center for Biotechnology, Acharya Nagarjuna University, Guntur 522 510, AP, India.


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Creative Commons License
© 2009 Krishna and Rao

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Center for Biotechnology, Acharya Nagarjuna University, Guntur 522 510, AP, India; Tel: +91 08632293400; Fax: +91 0863 2293378; E-mail: krssrao@gmail.com


Abstract

Stem cells are the centre for regenerative medicine. Given a right signal these undifferentiated cells have a remarkable potential to develop into specialized cell types (blood cells, heart cells etc.) in the human body. Stem cells, therefore, can be used in cell-based therapies to replace/repair damaged tissues and/or organs. Ongoing research in the area of stem cells focuses on their potential application (both embryonic stem cells and adult stem cells) to create specialized cells and replace the damaged ones. Hence, this cutting-edge technology might lead to new ways of detecting and treating diseases. Stem cell transplantation can be considered as an option for the treatment of certain type of cancers. This medical procedure can also be used to treat neurological diseases, autoimmune diseases, heart diseases, liver diseases, metabolic disorders, spinal cord injury etc. The present review, therefore, focuses on the growing use of stem cell transplantation in regenerative medicine to treat a variety of diseases. This review also provides the current status of the field with a particular emphasis on bone marrow transplantation.

Keywords: Bone marrow, leukemia, multiple myeloma, Parkinson’s disease, stem cell, transplantation.