Aluminium, Au, Be, Co, Cr, Cu, Hg, Ir, Ni, Pd, Pt, Rh and Ti represent causes of metal-induced allergic contact
dermatitis (ACD) which expresses in a broad spectrum of cutaneous adverse manifestations. The exposure is primarily by
skin contact with various items and products such as jewellery and piercing, cosmetics and tattoos, detergents, body implants
and dental prostheses. To reduce the growth of the metal ACD among people, the European Union issued directives
that limit the total Ni content in jewellery alloys and ban metals in cosmetics. Despite these regulations, the diffusion of
metal ACD remained quite high. On this basis, a review of the epidemiological evidence of the metal-induced ACD is reported
discussing the sources, the prevalence and the prescriptions.