The Open Dentistry Journal

ISSN: 1874-2106 ― Volume 14, 2020

Pulp Revascularization: A Literature Review

Pollyana Rodrigues de Souza Araújo1, Luciano Barreto Silva1, Alexandrino Pereira dos Santos Neto1, *, José Alcides Almeida de Arruda1, Pâmella Recco Álvares1, Ana Paula Veras Sobral1, Severino Alves Júnior2, Jair Carneiro Leão2, Rodivan Braz da Silva1, Gerhilde Callou Sampaio1
1 Department of Operative Dentistry and Endodontics, Dental College of Pernambuco, University of Pernambuco, Pernambuco, Brazil
2 Federal University of Pernambuco, Pernambuco, Brazil


Reestablishing blood flow and allowing the continuation of root development are some of the objectives of pulp revascularization. This procedure is currently indicated for teeth with incomplete root formation as an alternative to the traditional treatment of apecification, which consists of inserting calcium hydroxide paste into the root canal for a determined time period in order to induce the formation of a calcified barrier. Although it is considered as the most classically employed therapy, the permanence of the paste for long time periods may lead to the weakening of the root due to hygroscopic properties, as well as proteolytic activities of calcium hydroxide. Therefore, there has been a permanent search for alternatives which allow the full development of immature teeth. Revascularization has emerged as such an alternative, and a range of treatment protocols can be found in the scientific literature. The aim of this paper is to accomplish a literature review concerning this issue.

Keywords: Endodontics, therapeutics, calcium hydroxide, blood vessels.

Article Information

Identifiers and Pagination:

Year: 2017
Volume: 10
First Page: 48
Last Page: 56
Publisher Id: TODENTJ-11-48
DOI: 10.2174/1874210601711010048

Article History:

Received Date: 07/07/2016
Revision Received Date: 05/11/2016
Acceptance Date: 06/12/2016
Electronic publication date: 31/01/2017
Collection year: 2017

© Araújo et al.; Licensee Bentham Open

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Operative Dentistry and Endodontics, Dental College of Pernambuco, University of Pernambuco, General Newton Cavalcante 1650 Camaragibe-PE, Brazil, ZIP: 54753-901; Tel: +558134581000; Fax: +558134581186; E-mail:

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