The Open Dentistry Journal

ISSN: 1874-2106 ― Volume 14, 2020

Sealability of Different Root Canal Nanosealers: Nano Calcium Hydroxide and Nano Bioactive Glass

Asmaa A. Desouky1, *, Maged M. Negm2, Magdy M. Ali3
1 Department of Endodontics, Faculty of Dentistry, Assuit University, Assuit, Egypt
2 Department of Endodontics, Faculty of Oral and Dental Medicine, Cairo University, Giza, Egypt
3 Department of Endodontics, Faculty of Dental Medicine, Beni Suef University, Beni Suef, Egypt



The success of the endodontic treatment is largely dependent on the sealing achieved by root canal obturation. The application of sealer fills imperfections and increases adaptation of the root filling to the canal walls.


To evaluate the sealability of experimental nanosealers (nano calcium hydroxide and nano bioactive glass) and to compare it with the commercial zinc oxide eugenol sealer using a dye penetration method.

Materials and Methods:

Sixty single-rooted mandibular premolars were selected. The tooth crowns were removed so as to obtain standardized 15-mm-long root specimens. The root canal was instrumented with Protaper Ni-Ti rotary file and the final file size was up to # F4/.06 (in vitro study). They were then randomly allocated into 3 groups of 20 specimens each (n=20) according to the sealer used for obturation, and all samples were filled with single cone gutta-percha (#40/06) and one of the tested sealers. All teeth were coated with nail polish and then suspended in 2% methylene blue dye for 7 days. Stereo-microscope (x10) was used to evaluate the sealability of newly introduced nanosealers. The data were statistically analyzed by ANOVA test followed by post hoc analysis (P < 0.05).


Significant improvement shown by the presented study suggests that nano calcium hydroxide sealer showed significantly less dye leakage than nano bioactive glass sealer and zinc oxide eugenol sealer.


The results of this study showed that the synthesized nano-powder sealers are suitable for use in root canal therapy to prevent leakage.

The root canal can be sealed better by using smaller nano-powder particle sizes. In addition, the two groups exhibited significant differences in leakage in comparison with commonly used ZOE sealer.

Keywords: Dye penetration test, Nanosealers, Obturation, Sealability, Zinc Oxide, Protaper Ni-Ti rotary.

Article Information

Identifiers and Pagination:

Year: 2019
Volume: 13
First Page: 308
Last Page: 315
Publisher Id: TODENTJ-13-308
DOI: 10.2174/1874210601913010308

Article History:

Received Date: 27/05/2019
Revision Received Date: 17/07/2019
Acceptance Date: 05/08/2019
Electronic publication date: 30/08/2019
Collection year: 2019

Article Metrics:

CrossRef Citations:

Total Statistics:

Full-Text HTML Views: 939
Abstract HTML Views: 455
PDF Downloads: 223
ePub Downloads: 184
Total Views/Downloads: 1801

Unique Statistics:

Full-Text HTML Views: 526
Abstract HTML Views: 267
PDF Downloads: 163
ePub Downloads: 130
Total Views/Downloads: 1086
Geographical View

© 2019 Asmaa et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Borg Elsoror, Salah Salem Street, Tahta, Sohag, Egypt; Tel: 010 24022084; E-mail:


"Thank you for your magnificent and marvelous support throughout the publication stages. I would like to endorse my experience with you as a Junior Researcher and a recent graduate of the Dental school. Once again Thank you for your Great Help and Guidance throughout the stages of Publication. You guys are a great team and I am proud to be a Young Bentham author."

Asra Sabir Hussain
The University of Edinburgh Business School, UK

"My experience with Bentham Open was a valuable one because the quality of the services and analysis of my paper contributed in improving what we intended to convey to the readers."

José Ricardo Kina
Department of Surgery and Integrated Clinic,
Araçatuba School of Dentistry, São Paulo State University

"The Publication Manager was very cooperative and replied my mails and guided me without any delays; however the reviewing process was too long."

Mahtab Memarpour
Prevention of Oral and Dental Disease Research Center,
Department of Pediatric Dentistry, School of Dentistry,
Shiraz University of Medical Sciences, Shiraz,

Browse Contents

Webmaster Contact:
Copyright © 2020 Bentham Open