The Open Dentistry Journal

ISSN: 1874-2106 ― Volume 14, 2020

Microleakage and Resin-to-Dentin Interface Morphology of Pre-Etching versus Self-Etching Adhesive Systems Alternate Title: Microleakage and Resin-to-Dentin Interface Morphology

G.L Waldman, T.K Vaidyanathan*, J Vaidyanathan
NJ Dental School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA


The purpose of this study was to compare the microleakage and tissue-adhesive interface morphology from Class V restorations using different systems of dentin adhesives. Class V cavities were prepared on buccal surfaces of 27 extracted caries-free molars and premolars. Teeth were randomly assigned to one of three groups: (1) Prime & Bond NT, a 5th generation system using an initial step of total etch followed by a second step of application of a self bonding primer (2) Clearfil SE Bond, a 5th generation adhesive system employing two separate steps of self-etch priming and subsequent bonding (3) One-up Bond F, a 6th generation one step self-etching, self-priming and self-bonding adhesive. Microleakage and interface morphology of teeth restored with these adhesives and a composite resin were evaluated. Kruskal-Wallis Test (p = 0.05) was used to analyze the results. SEM analysis was used to relate interface morphology to microleakage. The mean and (SD) values of microleakage were: Prime and Bond NT: 0.15 (0.33), Clearfil SE Bond: 0.06 (0.17) and One-up Bond F: 2.96 (0.63). The mean microleakage for One-up Bond was significantly higher than for the other groups (p<0.05). Protruding tags in dentin channels were observed in Prime and Bond and Clearfil systems, but not in One-up Bond. The single step adhesive system, although more convenient for the clinician, uses a low viscosity formulation difficult to keep in place on cavity walls. It also tends to be too aggressive and hydrophilic to create an impermeable hybridized tissue-adhesive interfacial layer resistant to microleakage. Two-step adhesive systems, on the other hand, were retained on all segments of the cavosurface during application, and formed a hybridized interfacial layer resistant to microleakage.

Article Information

Identifiers and Pagination:

Year: 2008
Volume: 2
First Page: 120
Last Page: 125
Publisher Id: TODENTJ-2-120
DOI: 10.2174/1874210600802010120

Article History:

Received Date: 14/3/2008
Revision Received Date: 9/5/2008
Acceptance Date: 25/8/2008
Electronic publication date: 28/11/2008
Collection year: 2008

© Waldman et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Dept. of Restorative Dentistry, NJ Dental School, UMDNJ, Newark, NJ 07103, USA; Tel: (973) 972-6250; Fax: (973) 972-0370; E-mails:

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