REVIEW ARTICLE
Oral Microbiota Associated with Oral and Gastroenteric Cancer
D. Adriana G. Robayo1, Raquel F. Hernandez2, Alveiro T. Erira1, Ljubov Kandaurova2, Celia L. Juarez2, Victoria Juarez3, Angel Cid-Arregui2, *
Article Information
Identifiers and Pagination:
Year: 2020Volume: 14
First Page: 1
Last Page: 17
Publisher ID: TOMICROJ-14-1
DOI: 10.2174/1874285802014010001
Article History:
Received Date: 14/10/2019Revision Received Date: 15/12/2019
Acceptance Date: 18/12/2019
Electronic publication date: 10/2/2020
Collection year: 2020
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
When the normal microbiota-host interactions are altered, the commensal microbial community evolves to a dysbiotic status resulting in some species becoming pathogenic and acting synergistically in the development of local and systemic diseases, including cancer. Advances in genetics, immunology and microbiology during the last years have made it possible to gather information on the oral and gastrointestinal microbiome and its interaction with the host, which has led to a better understanding of the interrelationship between microbiota and cancer. There is growing evidence in support for the role of some species in the development, progression and responses to treatment of various types of cancer. Accordingly, the number of studies investigating the association between oral microbiota and oral and gastrointestinal cancers has increased significantly during the last years. Here, we review the literature documenting associations of oral microbiota with oral and gastroenteric cancers.