REVIEW ARTICLE
The Human Immune System toward Staphylococcus aureus
Rasoul Mirzaei1, Reza Ranjbar2, *, Sajad Karampoor3, Rezvan Goodarzi1, Hamze Hasanvand4
Article Information
Identifiers and Pagination:
Year: 2020Volume: 14
First Page: 164
Last Page: 170
Publisher ID: TOMICROJ-14-164
DOI: 10.2174/1874285802014010164
Article History:
Received Date: 20/02/2020Revision Received Date: 12/5/2020
Acceptance Date: 13/5/2020
Electronic publication date: 30/07/2020
Collection year: 2020
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
The immune system is responsible for protecting the host from pathogens, and it has evolved to deal with these pathogens. On the other hand, the co-evolution of pathogenic bacteria with hosts has led to the rise of an array of virulence genes that enable pathogen bacteria to evade or modulate the immune system. Staphylococcus aureus is a significant pathogen of humans that encodes several virulence factors that can modulate or evade from the innate and adaptive arm of the immune system. Overall, the immune reaction toward S. aureus contributes to stimulate innate and adaptive reactions. A profound understanding of the immune response to S. aureus infections will be critical for the development of vaccines and novel therapies. In this review, we summarized and discussed the novel information about the human immune system against S. aureus.