The Open Neurology Journal

ISSN: 1874-205X ― Volume 14, 2020

Brain Tumor in Differential Diagnosis of Seizures in Puerperium: Case Report

Luíza Guazzelli Pezzali3, *, Gabriela Francoes Rostirolla1, 3, Carina Bauer Luiz3, Lúcio Brandão Gomes4, Raquel Camara Rivero5, 6, Edimárlei Gonsales Valério1, 2, 3, Janete Vettorazzi1, 2, 3
1 Postgraduate Program in Health Sciences: Gynecology and Obstetrics, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brasil
2 Department of Gynecology and Obstetrics, Faculty of Medicine (FAMED), Universidade Federal do Rio Grande do Sul, Porto Alegre - Rio Grande do Sul (RS), Brasil
3 Service of Obstetrics and Gynecology, Hospital de Clínicas de Porto Alegre, Porto Alegre/RS, Brasil
4 Service of Neurosurgery, Hospital de Clínicas de Porto Alegre, Porto Alegre/RS, Brasil
5 Department of Pathology, Faculty of Medicine (FAMED), Universidade Federal do Rio Grande do Sul, Porto Alegre - Rio Grande do Sul (RS), Brasil
6 Service of Pathology, Hospital de Clínicas de Porto Alegre, Porto Alegre/RS, Brasil


Convulsive crisis is a transient disturbance of cerebral function, and the etiology of which may be manifold. Its clarification is essential for establishing adequate therapy and seizure control. In the pregnancy-puerperal cycle, eclampsia is the most common cause of it, but brain tumor, epilepsy and other disorders are part of the differential diagnosis. We report a case of seizure triggered by tumor in a primigest, 22 years old, at 38 weeks’ gestation with premature rupture of membranes. Cesarean section was performed due to non-reassuring fetal condition. On the second day of puerperium, she presented recurrent episodes of generalized tonic-clonic seizures and elevated blood pressure. She received magnesium sulfate for 24 hours and persisted with severe headache. Magnetic resonance imaging of the brain showed an expansive lesion in the left frontoparietal region. The patient underwent intracranial microsurgery on the eighth day after cesarean section, with complete resection of the lesion and anatomopathological diagnosis of schwannoma. She went through good postoperative evolution, without neurological deficits, and stayed on phenobarbital, with no seizures until 6 months of follow-up. From the case we conclude that although the first diagnosis in pregnant or puerperal women with seizures should be eclampsia, there are other causes, such as brain tumor and Posterior Reversible Encephalopathy Syndrome (PRES). Careful evaluation is required, especially in refractory cases and not responding to usual treatment.

Keywords: Seizure, Puerperium, Brain tumor, Eclampsia, Case report, Cerebral function.

Article Information

Identifiers and Pagination:

Year: 2019
Volume: 13
First Page: 67
Last Page: 71
Publisher Id: TONEUJ-13-67
DOI: 10.2174/1874205X01913010067

Article History:

Received Date: 25/10/2018
Revision Received Date: 13/03/2019
Acceptance Date: 04/04/2019
Electronic publication date: 30/04/2019
Collection year: 2019

© 2019 Pezzali et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Service of Obstetrics and Gynecology, Hospital de Clínicas de Porto Alegre, Porto Alegre/RS, Brasil;

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