State of the Art Review on Emerging Applications of Mesoporous Silica
Ajinkya Kailas Pote1, Vishal Vijay Pande1, *, Vipul Pralhadbhai Patel1, Mahendra Ashok Giri2, Aniket Uttam Pund3, Nitin Vijay Shelke3
1 Department of Pharmaceutics (PG), Sanjivani College of Pharmaceutical Education and Research, Kopargaon, Maharashtra 423603, India
2 Department of Pharmacology, Sanjivani College of Pharmaceutical Education and Research, Pune University, Kopargaon, Maharashtra 423603, India
3 Department of Pharmaceutics (PG), Sanjivani College of Pharmaceutical Education and Research, Pune University, Kopargaon, Maharashtra 423603, India
Abstract
The recent advances in the drug delivery system using a variety of technological platforms have resulted in innovation in the attitude towards diagnosis and therapeutics alike in the present times. Mesoporous Silica possesses favourable chemical properties, thermal stability, and biocompatibility. The unique structure of mesoporous silica makes possible the effective loading of drugs and their subsequent release in a controlled manner at the target site. The properties like pore size, high drug loading, and porosity as well as the surface properties of Mesoporous silica make them a suitable platform for many drug delivery applications. This review focuses on the applications and the advances made in the mesoporous silica to broaden the spectrum of its use especially in the field of medicine. The Mesoporous Silica carrier has proved its use in the field of biosensing, controlled and targeted drug release, gene delivery, water treatment, solubility and bioavailability enhancement and wound healing.
Keywords: Mesoporous Silica, Theranostic, Biocompatible, Biodegradable, Biosensing, Drug delivery system.
Article Information
Article History:
Received Date: 02/04/2020
Revision Received Date: 15/08/2020
Acceptance Date: 16/08/2020
Electronic publication date: 22/10/2020
Collection year: 2020
© 2020 Pote et al.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at:
https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
* Address correspondence to this author at the Department of Pharmaceutics, Sanjivani College of Pharmaceutical Education and Research, Kopargaon, Maharashtra 423603, India; Tel: 9623443179, E-mail: drvishalpande@gmail.com
Open Peer Review Details |
Manuscript submitted on 02-04-2020 |
Original Manuscript |
State of the Art Review on Emerging Applications of Mesoporous Silica |