RESEARCH ARTICLE


Maximising Refractive Outcomes with an Extended Depth of Focus IOL



Barry Power1, 2, *, Rory Murphy1, 2, Antonio Leccisotti2, 3, Tara Moore2, William Power4, Paul O’Brien4
1 Department of Ophthalmology, Mater Misericordiae University Hospital, Dublin, Ireland
2 Department of Ophthalmology, Biomedical Sciences Research Institute, Ulster University, Northern Ireland
3 Department of Ophthalmology, University of Siena, Siena, Italy
4 Blackrock Clinic, Dublin, Ireland


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Creative Commons License
© 2018 Power et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Ophthalmology, Mater Misericordiae University Hospital, Dublin, Ireland; Tel: 0877902040; Email: Barry.power.1@ucdconnect.ie


Abstract

Objective:

To assess the impact of the magnitude of preoperative and postoperative corneal astigmatism on refractive outcomes in patients undergoing cataract surgery or lens exchange with an extended depth of focus intraocular lens. To compare visual outcomes of steep and temporal on-axis corneal incisions.

Setting:

Department of Ophthalmology, Blackrock Clinic, Dublin, Ireland.

Design:

Prospective cohort analysis.

Methods:

Fifty-three consecutive adult patients (94 eyes) undergoing routine phacoemulsification with Symfony IOL implantation were analysed. Exclusion criteria: targets for mini-monovision, incomplete data, other ocular pathology. Data were prospectively collected on pre- and postoperative refraction, keratometry, distance vision, near vision, surgical wound site and Surgically Induced Astigmatism (SIA).

Results:

The average postoperative monocular Uncorrected Distance and Near visual acuities (UDVA and UNVA) were 0.12 LogMAR (± 0.1) (6/7.5+1) and 0.34 LogMAR (± 0.09) respectively. The average binocular UDVA and UNVA were 0.05 (± 0.07) and 0.29 LogMAR (± 0.06) respectively. Low levels of preoperative corneal astigmatism (0-0.99 D) were associated with better LogMAR UDVA and UNVA when compared with higher levels (> 0.99 D): 0.11 (CI 0.103-0.107) vs. 0.206 (CI 0.122-0.290) (p =0.015, CI 95%) and 0.33 (CI 0.316 - 0.356) vs. 0.39 (CI 0.34-0.43) (p =0.034, CI 95%) respectively. When patients with steep on-axis corneal incisions were compared with temporal on-axis corneal incisions, no difference was detected in visual outcome or SIA.

Conclusion:

The Symfony IOL is an effective surgical means of addressing presbyopia and reducing postoperative spectacle dependence. We stress caution when offering potential spectacle independence for patients with over 1D of preoperative corneal astigmatism as these patients achieve statistically significantly inferior and less predictable visual results.

Keywords: Cataract surgery, Corneal astigmatism, Refractive surgery, Symfony IOL, Extended depth of focus IOL, SIA.