The Open Ophthalmology Journal

ISSN: 1874-3641 ― Volume 14, 2020

Single-Session Low Duration Panretinal Photocoagulation Using Conventional Laser on Central Subfield Macular Thickness in Diabetic Retinopathy

Arief S Kartasasmita*, Prettyla Yollamanda, Grimaldi Ihsan, Rova Virgana
Department of Ophthalmology, Universitas Padjadjaran / Cicendo National Eye Hospital, Jl. Cicendo No. 4, Bandung, Indonesia



To compare the change in central subfield macular thickness following single-session and multiple-session laser panretinal photocoagulation in subjects with diabetic retinopathy.


A single-center, randomized controlled trial study was performed on 28 eyes of 16 patients with severe non-proliferative diabetic retinopathy or proliferative diabetic retinopathy. Eyes were randomly assigned for treatment with panretinal photocoagulation performed either in single-session or multiple-session divided into three sessions during two-week period. Central subfield macular thickness was quantified using spectral domain optical coherence tomography and changes at four weeks follow-up were compared to the baseline measurement.


Mean baseline central subfield macular thickness of 12 eyes underwent single-session and 16 eyes underwent multiple-session panretinal photocoagulation were 342.91+109.51 micrometers and 354+171.79 micrometers (p> .05), respectively. Mean post laser central subfield macular thickness in the single-session group was 305.83+ 81.95 micrometers and 389.75 + 229.51 micrometers in the multiple-session group (p > .05). Mean central subfield macular thickness changes four weeks post laser was 37.08 + 94.21 micrometers for eyes treated with single-session and -35.75+123.62 micrometers for the multiple-session treated eyes (p = .101).


There was no significant difference in change of central subfield macular thickness at four weeks post laser from treatment with single-session and multiple-session panretinal photocoagulation. Single-session panretinal photocoagulation can be used as effective multiple-session panretinal photocoagulation for the treatment of diabetic retinopathy.

Keywords: Diabetic retinopathy, Panretinal photocoagulation, Central subfield macular thickness, DRI, ETDRS, Conventional Laser.

Article Information

Identifiers and Pagination:

Year: 2018
Volume: 12
First Page: 308
Last Page: 313
Publisher Id: TOOPHTJ-12-308
DOI: 10.2174/1874364101812010308

Article History:

Received Date: 10/6/2018
Revision Received Date: 25/10/2018
Acceptance Date: 3/11/2018
Electronic publication date: 28/12/2018
Collection year: 2018

© 2018 Kartasasmita et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: ( This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Department of Ophthalmology, Universitas Padjadjaran / Cicendo National Eye Hospital, Jl. Cicendo No. 4, Bandung, Indonesia; Tel: +62 22 4321280-81; E-mail:

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