Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess
L. Jay Katz*, Oana Stirbu, Garth Willis, Parul Ichhpujani
Wills Eye Institute, 840 Walnut Street, Philadelphia, USA
We present a 78-year-old patient who developed refractory glaucoma following a fungal infection of the corneal incision after cataract extraction with posterior chamber intraocular lens implantation. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was performed to improve the trabecular meshwork outflow facility compromised secondary to fibrin blockade. The intraocular pressure dropped dramatically from 48 mmHg to 10 mmHg postoperatively, negating the need for glaucoma surgery.
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* Address correspondence to this author at the Glaucoma service, Wills Eye Institute, 840 Walnut Street, Philadelphia, USA; Tel: 215-285-8148; Fax: 215- 928-3903; E-mail: email@example.com