Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess

Katz, L. Jay; Stirbu, Oana; Willis, Garth; Ichhpujani, Parul

Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess

L. Jay Katz^*, Oana Stirbu, Garth Willis, Parul Ichhpujani

Wills Eye Institute, 840 Walnut Street, Philadelphia, USA

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Identifiers and Pagination:

Year: 2009
Volume: 3
First Page: 75
Last Page: 76
Publisher ID: TOOPHTJ-3-75
DOI: 10.2174/1874364100903010075

Article History:

Received Date: 11/6/2009
Revision Received Date: 23/7/2009
Acceptance Date: 31/8/2009
Electronic publication date: 25/9/2009
Collection year: 2009

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© Katzet al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

^* Address correspondence to this author at the Glaucoma service, Wills Eye Institute, 840 Walnut Street, Philadelphia, USA; Tel: 215-285-8148; Fax: 215- 928-3903; E-mail: ljk22222@aol.com

We present a 78-year-old patient who developed refractory glaucoma following a fungal infection of the corneal incision after cataract extraction with posterior chamber intraocular lens implantation. An anterior chamber injection of 0.1 ml recombinant tissue plasminogen activator (25 mcg/0.1 mL) was performed to improve the trabecular meshwork outflow facility compromised secondary to fibrin blockade. The intraocular pressure dropped dramatically from 48 mmHg to 10 mmHg postoperatively, negating the need for glaucoma surgery.

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RESEARCH ARTICLE

Intracameral Recombinant Tissue Plasminogen Activator for Refractory Glaucoma Secondary to a Fungal Corneal Abscess

Article Information

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Abstract

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