LETTER
Oral COVID-19 Disclosing Test: A Novel Rapid Technique in Infection Diagnosis
Rachid Ait Addi1, *, Abdelhafid Benksim1, Mohamed Cherkaoui1
Article Information
Identifiers and Pagination:
Year: 2020Volume: 13
First Page: 455
Last Page: 458
Publisher ID: TOPHJ-13-455
DOI: 10.2174/1874944502013010455
Article History:
Received Date: 24/4/2020Acceptance Date: 24/4/2020
Electronic publication date: 22/09/2020
Collection year: 2020
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
COVID-19 is an acute respiratory disease caused by novel coronavirus SARS-CoV-2 or 2019-nCoV. Recently, on March 11, 2020, COVID-19 was declared by the WHO as a virus pandemic disease. Nucleic acid real time polymerase chain reaction (PCR) test has become the standard method for diagnosis of SARS-CoV 2 infection; these real time PCR test kits have many limitations. Antibody tests are expensive and not available, especially in the developing countries. There is an urgent need for an accurate and rapid test method to quickly identify a large number of infected patients and asymptomatic persons, and also which can be available all over the world. We propose a new test technique based on the use of oral gel, mouthwash, or tablets that color the area where the virus is localized in mouth, to diagnose the COVID-19 infection. In fact, our test is composed of specific COVID-19 antibody IgM and IgG coupled to colorful or fluorescent molecules. As of April 2020, the study is waiting to be funded and clinical trials will be prepared to be lunched to get advantage of the technique in order to improve COVID-19 testing.
