Table 2: Allosteric Amino Acid Residues Involved in the Binding Interactions with the Ligands

Residues involved in hydrogen bond Residues involved in hydrophobic interaction (small domain) Residues involved in hydrophobic interaction (large domain)
Arg63, Tyr215, Gln98 Val452, Val455, Ala456 Val62, Pro66, Ile159, Met210,Ile211, Tyr214, Met235, Cys220