Table 1: Summary of Fold Change and Z’ Value of Four Different Receptors Known to Couple with Different G Protein Pathways, Measured by Individual Luciferase Reporter Assays

Luciferase Reporter	Receptor	G-protein subunit	Fold change	Z’ in 384-well
CRE-luc2P	DRD1	Gαs	366	0.78
NFAT-RE-luc2P	M3R	Gαq	49	0.79
SRE-luc2CP	M4R	Gαi	11	0.85
SRF-RE-luc2P	EDG receptor	Gα12	127	0.83