Table 2: Comparison of EC50 of Agonist-Induced Activation of m3 Muscarinic Receptor or of Endogenous β2-Adrenergic Receptor Measured by Four Luciferase Reporter Assays
| RE |
M3R (M) |
β2AR (M) |
| CRE |
> 1.6 × 10-4
|
9.2 ×10-8
|
| NFAT-RE |
8.0 × 10-8
|
N/A |
| SRE |
1.2 × 10-7
|
N/A |
| SRF-RE |
9.2 × 10-8
|
N/A |