| Demethylase | Domains in structure | Ligands | PDB code | References |
|---|---|---|---|---|
| JMJD2A | JMJ | H3K9Me3/2/1, NOG | 2OS2, 2OT7, 2OX0 | [15] |
| JMJ | 2,4-PDCA | 2VD7 | - | |
| JMJ | Oxalyltyrosine derivative | 2WWJ | [48] | |
| JMJ | 5C-8HQ | 3NJY | [51] | |
| Tandem Tudor | H3K4Me3 | 2GFA | [52] | |
| Tandem Tudor | H4K20Me3 | 2QQS | [53] | |
| JMJD2C | JMJ | NOG | 2XML | - |
| Tudor | - | 2XDP | - | |
| JMJD2D | JMJ | NOG | 3DXU | - |
| JMJD3 | JMJ | 8HQ-5CA | 2XXZ | - |
| FBXL11(hJHDM1A) | JMJ | 2-OG | 2YU1 | - |
| PHF8 | JMJ | H3K4Me3K9Me2, NOG | 3KV4 | [16] |
| KIAA1718 | JMJ | NOG | 3KV5 | [16] |
| LSD1 | LSD1-CoREST | FAD + H3K4Me2 suicide substrate | 2UXN | [41] |
| LSD1-CoREST | FAD + trans-2-Phenylcyclo-propylamine | 3XAF, 3XAG, 3XAH, 3XAJ, 3XAQ, 3XAS | [54] |