Table 1: Hill Slopes, IC50s, and Maximum Inhibition were Calculated for each of the 3 Reproducible Hits in the Presence of Full-Length AMPK and the Regulatory Fragment (Data in Parentheses).

Positive hit	Vendor, Catalog Number	Structure	Hill Slope	IC50, µM
1	Vitas-M Laboratory, Ltd., STK740822		1.4 (1.4)	2.9 (1.6)
2	Vitas-M Laboratory, Ltd., STL035166		1.3 (1.4)	2.7 (1.5)
3	Enamine, Ltd., Z64358107		1.1 (2.6)	0.3 (0.2)