Entry | Base | Solvent | Time (min) | Yieldb (%) |
---|---|---|---|---|
1 | Diethylamine | Ethanol | 120 | 50 |
2 | Diethylamine | Methanol | 130 | 30 |
3 | Diethylamine | Acetic acid | 150 | 35 |
4 | Diethylamine | DCM | 110 | 40 |
5 | Diethylamine | Toluene | 140 | 30 |
6 | Triethylamine | Ethanol | 100 | 65 |
7 | Triethylamine | Methanol | 110 | 40 |
8 | Triethylamine | Acetic acid | 130 | 30 |
9 | Triethylamine | DCM | 120 | 45 |
10 | Triethylamine | Toluene | 125 | 35 |
11 | Potassium carbonate | Ethanol | 30 | 90 |
12 | Potassium carbonate | Methanol | 40 | 80 |
13 | Potassium carbonate | Acetic acid | 60 | 80 |
14 | Potassium carbonate | DCM | 50 | 85 |
15 | Potassium carbonate | Toluene | 70 | 75 |