Table 7: Lethal concentration (IC50) of the macrocyclic metal complexes on MCF-7 and Hep-G2 cell lines.

No Compound IC50(µg/mL)a
MCF-7 Hep-G2
1 [FeLCl2].1/2EtOH.1/2H2O 2.5 3.0
2 [CoLCl (OH)]. H2O 2.2 2.7
5 [NiLCl.H2O] Cl.H2O.1/2EtOH 1.6 1.7
7 [CuLCl2].2H2O 3.2 3.7
9 [CuL(OH)]NO3.H2O 2.2 2.5

a : IC50 is the concentration of compound (in µg/mL) that inhibits a proliferation rate of the tumor cells by 50% as compared to control untreated cells.