| Cell Type and IC50 Value | Phthalate | Natural Source of the Phthalate | Extracted Part of the Organism | Reference |
|---|---|---|---|---|
| CHO (ATCC; CCL-61) IC50 = 36±8.6 μg/mL | Di-n-butyl phthalate (5) | Streptomyces albidoflavus | broth extract | N. Roy et al., 2006 [217] |
| CHO (ATCC; CCL-61) IC50 = 193±5.4 μg/mL | Bis(2-ethylhexyl) phthalate (9) | Streptomyces albidoflavus | broth extract | N. Roy et al., 2006 [217] |
| DU145 (ATCC; HTB-81) IC50 = 31.23±8.7 μg/mL | Di-n-butyl phthalate (5) | Streptomyces albidoflavus | broth extract | N. Roy et al., 2006 [217] |
| DU145 (ATCC; HTB-81) IC50 = 33.46±7.7 μg/mL | Bis(2-ethylhexyl) phthalate (9) | Streptomyces albidoflavus | broth extract | N. Roy et al., 2006 [217] |
| HEK293 (ATCC; CRL- 1573) IC50 = 19.77±10 μg/mL |
Di-n-butyl phthalate (5) | Streptomyces albidoflavus | broth extract | N. Roy et al., 2006 [217] |
| MCF-7 (ATCC; HTB-22) IC50 = 32.43±3.6 μg/mL | Di-n-butyl phthalate (5) | Streptomyces albidoflavus | broth extract | N. Roy et al., 2006 [217] |
| MCF-7 IC50 = 0.13 mM | Di-n-octyl phthalate (20) | Pachygone ovata (Poir.) Miers | L.E. Amalarasi and G.J. Jothi, 2019 [150] | |
| MCF-7 (ATCC; HTB-22) IC50 = 46.55±0.1 μg/ml | Bis(2-ethylhexyl) phthalate (9) | Streptomyces albidoflavus | broth extract | N. Roy et al., 2006 [217] |
| MCF-7 IC50 = 69.2 μM | Bis(2-methylheptyl) phthalate (36) | Phyllanthus pulcher | G. Bagalkotkar, 2007 [177] | |
| Toxicity against brine shrimp Artemia salina larvae LC50 = 2800 μg/mL | Bis(2-ethylhexyl) phthalate (9) | Streptomyces ruber EKH2 | broth extract | K.M. Barakat and E.A. Beltagy, 2015 [305] |