Table 1: Sample characteristics in 518 children and adolescents with ADHD.

Total Sample Sex ADHD subtype Age of onset*
Boys Girls p IA C p Children Adolescents p
Age mean (SD) years 11.40 (3.3) 11.38 (3.2) 11.5 (3.69) > .1 11.9 (3.4) 11.2 (3.2) .027* 8.9 (1.7) 14.6 (1.8) <.001
Follow-up, months 33 (22.7) 32.4 (23.2) 35.3 (20.7) > .1 31.4 (20.8) 33.7 (23.6) > .1 37.7 (25.1) 27 (17.7) <.001
ADHD-RS-IV.es
T1 ADHD-RS-IV (SD) 29.9 (10.42) 30.71 (10.5 26.7 (9.6) <.001 28.82 (10.6) 30.4 (10.3) 31.7 (10) 27.6 (10.3)
Inattention score 17.85 (5.47) 18.2 (5.4) 16.6 (5.4) <.001 17.4 (5.8) 18 (5.3) >.1 17.9 (5.4) 17.8 (5.5) > .1
Hyperactive score 8.76 (6.0) 12.5 (7.1) 10.1 (6.4) <.001 11.4 (7.2) 12.3 (6.9) >.1 13.8 (6.8) 9.8 (6.7) <.001
T2 ADHD-RS-IV (SD) 23.33 (14.19) 24.2 (14.5) 20 (12.6) <.001 23.6 (15.7) 23.2 (13.4) 24.3 (14.1) 22 (14.2)
Inattention score 14.60 (8.7) 15.2 (8.9) 12.3 (7.6) <.001 14.8 (9.9) 14.5 (8.2) >.1 15.1 (8.6) 14 (8.7) > .1
Hyperactive score 8.76 (6.0) 9 (6.1) 7.7 (5.6) <.001 8.9 (6.5) 8.7 (5.8) >.1 9.2 (6) 8 .1 (6) .049
T1-T2 ADHD-RS-IV <.001 <.001
SNAP-IV
T1 ODD score 10.08 (4.47) 10.1 (4.5) 8.7 (4.7) <.001 9.3 (4.7) 10.1 (4.5) >.1 9.9 (4.7) 9.9 (4.7) > .1
T2 ODD score 6.36 (5.0) 6.7 (5) 4.8 (4.5 <.001 6.2 (4.9) 6.4 (4.9) >.1 6.7 (5) 5.9 (5) > .1
T1-T2 ODD score <.001 <.001 <.001
CGI-S
T1 CGI-S 3.85 (0.77) 3.9 (0.8) 3.7 (0.8) .09 3.9 (0.7) 3.8 (0.8) >.1 3.8 (0.8) 3.9 (0.8) >.1
T2 CGI-S 2.71 (0.94) 2.7 (0.9) 2.6 (0.9) .06 2.7 (0.9) 2.7 (0.9) >.1 2.8 (0.9) 2.8 (0.9) .009
T1-T2 CGI-S <.001 <.001 <.001

Note: ADHD = Attention-deficit/hyperactivity disorder. ADHD subtype presentation: IA (inattentive); C (Combined). ADHD-RS-IV.es: ADHD rating scale-IV (Spanish version). ODD: oppositional defiant disorder CGI-S: Clinical Global Impressions Severity Scale. T1: baseline; T2: end point-last follow-up visit. p<0.005: statistically significant *Children (<11.9y), Adolescents (12-18y)