| Item | Case | Control | P Value |
|---|---|---|---|
| Number | 34898 | 69796 | |
| Initial age (mean ±SD) | 46.6±14.9 | 47.4±16.1 | .004 |
| Gender | .49 | ||
| Male | 18116 (51.9%) | 35833 (51.3%) | |
| Female | 16782 (48.1%) | 33963 (48.7%) | |
| Marital Status | .07 | ||
| Single | 15949 (45.7%) | 32734 (46.9%) | |
| Married | 16204 (46.4%) | 31897 (45.7%) | |
| Divorced | 2745 (7.9%) | 5165 (7.4%) | |
| Smoking Status | .006 | ||
| Smoker | 12179 (34.9%) | 23172 (33.2%) | |
| Non-Smoker | 22719 (65.1%) | 46624 (66.8%) | |
| Comorbidity at index date | |||
| DM | 7503 (21.5%) | 15913 (22.8%) | .003 |
| CKD | 227 (0.7%) | 349 (0.5%) | .04 |
| CVD | 8478 (24.3%) | 16122 (23.1%) | .08 |
| Liver disorder | 294 (0.8%) | 768 (1.1%) | .04 |
| Tremor history | 147 (0.4%) | 244 (0.3%) | .12 |
| Other movement disorder | 196 (0.6%) | 351 (0.5%) | .13 |
| Medication used before index date | |||
| Antipsychotics | 516 (1.5%) | 1117 (1.6%) | .09 |