Item |
HR (95% CI) |
P value |
Gender (ref: male) |
1.00 |
|
Female |
2.6 (1.3-3.7) |
.09 |
Age (per 1 year) |
1.1 (0.8-1.2) |
.003 |
Smoking Status (ref: non-smokers) |
1.00 |
|
Smokers |
1.7 (1.3-2.2) |
.02 |
Comorbidity at index date (ref: without) |
1.00 |
|
DM |
1.2 (0.9-1.4) |
.3 |
CKD |
1.4 (1.1-1.6) |
.5 |
CVD |
1.6 (1.2-2.3) |
.1 |
Liver disorder |
0.7 (0.6-1.2) |
.9 |
Tremor history |
7.4 (5.9-8.3) |
.002 |
Other movement disorder |
3.2 (2.7-4.3) |
.001 |
Intervention (ref: Citalopram) |
1.00 |
|
Amitriptyline |
1.2 (0.8-3.7) |
.001 |
Clomipramine |
2.4 (1.7-4.3) |
.0003 |
Fluoxetine |
0.7 (0.4-1.3) |
.006 |
Fluvoxamine |
4.9 (3.7-5.9) |
.0001 |
Imipramine |
8.3 (7.1-10.5) |
.001 |
Nortriptyline |
4.1 (2.8-6.4) |
.03 |
Paroxetine |
8.6 (7.4-9.8) |
.0002 |
Medication used before index date ( ref: no antipsychotics) |
1.00 |
|
Antipsychotics |
3.9 (2.5-4.6) |
.001 |