Scientist Reported Data |
Inflammatory Mediators and Assessing Parameters |
Associated Diseases | Study Conducted on Animal / Cell Culture | Study Conducted on Human | Inference | |
---|---|---|---|---|---|---|
Duration of Study (Year) | Sample Size | |||||
Nadrowski et al.(2010) [86] | Interleukin 6 (IL 6) | Atherosclerosis | NA | 2007- 2011 | 4979 | For systematic inflammation IL-6 is important biomarker and is responsible for atherosclerosis. |
Henry et al.(2008) [87] | Interleukin -6 (IL- 6) | Depression | BV-2 microglia and Male BALB/c mice |
NA | NA | Decrease levels of IL-6 in blood cause behavioral changes. |
Zhang et al. (2014) [88] | NLRP3 inflammasome | Depression | Male BALB/c mice | NA | NA | NLRP3 inflammasome is responsible for depressive behaviors. |
Grivennikov et al. (2009) [89] | Interleukin -6 (IL- 6) | Lung cancer | Stat3F/F mice | NA | NA | Destruction of IL-6 trans-signaling delays growth of tumor. |
Lin et al.(2017) [90] | Interleukin 6(IL 6) | Hepatocellular carcinoma | Rag1−/− mice And Rarres2−/− mice |
Elevated level of IL-6 leads to progression of lung cancer. |