Table 3: Parameters measured after 1 hour from the start of treatment.
After one hour |
Group C (n = 25)
|
Group M (n = 25)
|
Tests |
Mean |
± |
SD |
Mean |
± |
SD |
t/X2
|
P-value |
RR (cycles/min) |
25.84 |
± |
3.15 |
21.35 |
± |
3.5 |
4.768 |
< 0.001** |
PaO2 (mmHg) |
72.67 |
± |
4.38 |
81.24 |
± |
5.09 |
6.381 |
< 0.001** |
SpO2
|
93.24 |
± |
6.72 |
93.56 |
± |
7.54 |
0.158 |
0.874 |
pH |
7.25 |
± |
0.07 |
7.29 |
± |
0.09 |
1.754 |
0.085 |
PaCO2 (mmHg) |
43.84 |
± |
4.8 |
44.35 |
± |
5.1 |
0.364 |
0.717 |
No. requiring MV |
9/16 (36%) |
3/22 (12%) |
3.947 |
0.047* |
Data are presented as mean±standard deviation. Number of patients requiring mechanical ventilation expressed as percentage. Group C: standard pharmacotherapy and placebo, Group M: standard pharmacotherapy and 25 μg milrinone slow IV bolus, MV: mechanical ventilation, RR: respiratory rate, PaO2: arterial partial pressure of oxygen, SpO2: arterial oxygen saturation, pH: potential of hydrogen, PaCO2 arterial partial pressure of carbon dioxide.
**Statistically highly significant
*Statistically significant