Importance of CDK7 for G1 Re-Entry into the Mammalian Cell Cycle and Identification of New Downstream Networks Using a Computational Method

Fig. (3) Networks identified for the G1/S course data (A) and the isolated linkages associated with nodal genes Ccna2 (B), Egfr (C), Fgf3 (D) and Trp53 (E). Red arrows indicate linkages associated with upregulation and blue arrows indicate linkages associated with downregulation for any two genes within the network. Bold lines indicate linkages with nodal genes.