Importance of CDK7 for G1 Re-Entry into the Mammalian Cell Cycle and Identification of New Downstream Networks Using a Computational Method

Table 4.: Summary of the Results from the MCMC Analyses

Parent	Target	Mean	Std.	Percent <0
G0 Network
Cdk7	Ccna2	-6.0037	0.0718	0
	Egfr	-2.5725	0.0265	0
	Etv6	2.0637	0.0279	0
	Figf	1.4832	0.0022	0
	Ll1a	-1.0015	1.0882	17.9
	Mybl2	-2.8674	0.0141	0
	Nmyc1	-0.712	0.0064	0
	Nras	-2.8768	0.0626	0
	Rgf	6.7274	0.0059	0
	Rbl1	1.9701	0.0065	0
G1 Network
Trp53	Abl1	0.9456	0.4592	0.0225
	Cdk7	-3.7324	0.0008	0
	Elk1	6.7449	1.3828	0.004
	Ll1a	-1.5102	0.0721	0
	Nmyc1	6.1901	0.0417	0
	Rbl1	-6.6934	0.3521	0
	Ret	1.7052	2.7057	25.7

For G0 data, MCMC sampling was performed 140,000 times and the mean, standard deviation (Std.) and percentage below zero were assessed from the last 70,000 samplings. If the number was negative, only the samples above zero were counted. For G1 data, MCMC sampling was performed 300,000 times and the mean, Std., and percentage below zero were assessed from the last 150,000 samplings.