Fig. (1) Inhibition of HBMEC capillary length and abundance by aldosterone and eplerenone. HBMEC (30,000 cells) were exposed to 100 nM aldosterone (b), 400 nM eplerenone (c), or the agonist plus the antagonist (d), for 18 h and thereafter layered on Matrigel for 18 h. Archimed program of Microvision was used to quantitate the capillary length (arrows in a) and the number of networks (*) compared to control (a) in Fig. (1).