bBased on the criteria of excellence of systematic reviews that resulted in the 11 domains examined by the AMSTAR, the overall score on the R-AMSTAR, which is revised only to the extent that it produces a quantification of the assessments of these domains, reveals the possibility to assign a grade of systematic review quality and clinical relevance, based on the criteria of the top percentile of the scores reflecting an A paper, and so on. The rankings are, for obvious reasons, relative strictly to the systematic reviews examined in response to the specific P.I.C.O. question, and thus pertain to a fixed (rather than random) interpretative model.