Table 1: CYP1A Enzyme Similarity for Global Metabolisms of Steroid and PAH Substrates
Human CYP1A1
Human CYP1A2
Mouse CYP1A1
Rabbit CYP1A2
Human CYP1A1
Human CYP1A2
1 / 2
Mouse CYP1A1
76 / 65
13 / 21
Rabbit CYP1A2
29 / 9
8 / 95
54 / 25
100 /100
For each two CYP1A enzymes compared, the left number is the percentage of similarity for steroid activities measured from their distance in the MDS plot, and the right number is
the percentage of similarity for PAH activities. The 100 % was set from the average within-cluster distances measured with duplicate assays.