| Level of Fasting Insulin Secretion |
Insulinopenia 0 à10µU/ml N=53 (53%) |
Insulin resistance 10 à 20µU/ml N= 30 (30%) |
Hyperinsulinisme >20µU/ml N= 17(17%) |
P-value |
|---|---|---|---|---|
| Associated characteristics | ||||
| Sex | H 18 (33%) F 36 (67%) |
H 6 (20%) F 24 (80%) |
H 4 (24%) F 13 (76%) |
0.389 |
| Age (years) | 59.87±9.92 | 61.40±9.58 | 55.00±8.02 | 0.084 |
| Glycemia (g/l) | 1.976±0.940 | 1.788±0.801 | 2.100±0.973 | 0.483 |
| Insulin/glycemia | 10.79±7.54 | 24.06±14.86 | 62.2±42.3 | 0.000 |
| Peptide C | 0.1873±0.1754 | 1.1937±0.2571 | 3.405±1.744 | 0.000 |
| Glycated hemoglobin (%) | 7.593±1.152 | 7.699±1.033 | 7.677±1.200 | 0.908 |
| HOMA-IR | 1.458±1.607 | 2.357±1.577 | 5.247±3.759 | 0.000 |
| Β% | 44.42±49.23 | 64.86±53.16 | 104.3±101.1 | 0.007 |
| S% | 95.75±41.48 | 48.95±12.65 | 23.83±8.49 | 0.000 |
| BMI | 29.873±4.949 | 31.04±6.70 | 29.53±7.01 | 0.609 |
| Waist circumference (cm) | 104.11±13.86 | 106.67±13.02 | 102.71±19.59 | 0.628 |
| Consanguinity | Yes 25 (46%) No 29 (54%) |
Yes 17 (57%) 13 (43%) |
Yes 8 (47%) 9 (53%) |
0.644 |
| Heredity in diabetes | Yes 29 (54%) No 25 (46%) |
Yes 18 (60%) No 12 (40%) |
Yes 8 (47%) No 9 (53%) |
0.684 |
| Smoking | Yes 10 (19%) No 44 (81%) |
Yes 5 (17%) No 25 (83%) |
Yes 4 (24%) No 13 (76%) |
0.843 |
| Triglycerides (mg/dl) | 2.176±1.525 | 2.165±1.608 | 3.012±2.307 | 0.183 |
| Total Cholesterol (mg/dl) | 1.8517±0.4724 | 1.6800±0.3814 | 1.9065±0.4085 | 0.142 |
| HDL-Cholesterol (mg/dl) | 0.4496±0.1518 | 0.4113±0.1213 | 0.3965±0.1069 | 0.265 |
| LDL-Cholesterol (mg/dl) | 1.0624±0.3732 | 0.9277±0.3212 | 0.9806±0.2580 | 0.213 |
| Non HDL-Cholesterol (mg/dl) | 1.4020±0.4771 | 1.2687±0.3879 | 1.510±0.438 | 0.183 |
| Triglyceride /HDL (mg/dl) | 5.530±4.807 | 5.544±4.265 | 8.45±7.71 | 0.119 |
| CRP | 5.481±3.226 | 10.87±34.23 | 4.471±1.231 | 0.384 |
| Arterial ypertension | Yes (22%) No (78%) |
Yes (20%) No (80%) |
Yes (12) No (88%) |
0.640 |
| DBP (mmHg) | 6.852±0.998 | 6.667±1.184 | 7.118±1.166 | 0.392 |
| SBP (mmHg) | 12.926±1.747 | 13.067±1.741 | 12.000±1.768 | 0.109 |