Table 8: ‘Naїve Bayes’ Calculation

Syndrome Name No of Cases Sensitivity Specificity Predictive Value
FAS 3597 99.9 99.5 99.9
Trisomy 21 702 100.0 100.0 100.0
Fragile X 355 99.4 99.7 95.7
Noonan 299 100.0 100.0 100.0
Congenital CMV 221 95.5 99.9 97.7
Trisomy 18 208 100.0 99.9 98.1
Turner 123 95.9 100.0 99.2
Trisomy 13 93 95.7 100.0 100.0
deLange 81 100.0 100.0 100.0
Williams 66 97.0 100.0 100.0
Beckwith 56 100.0 100.0 100.0
Prader-Willi 55 100.0 100.0 98.2
Meckel 38 97.4 100.0 100.0
Cri du chat (5p-) 30 100.0 100.0 100.0
Zellweger 30 100.0 100.0 100.0
Klippel-Feil 23 95.7 100.0 100.0
SLOS 23 100.0 100.0 95.8

FAS, fetal alcohol syndrome, SLOS, Smith-Lemli-Opitz syndrome. Average of ten runs of 6000 artificial patients in each run. On average correctly diagnosed 5971, global error rate 0.48%.