Table 3: Mean I50 Metrics from a Number of Studies [2, 16-18] Showing the Dependence of Behaviour on Diabetic Progression

Published Findings Total I50 Mean (N) NGT I50 Mean (N) IFG-T2DM I50 Mean (N) Protocol
Current analysis 139 (33) 107 (23) 226 (10) Dynamic
Natali et al. [2] 293 (7) 240 (4) 364 (3) Stepped EIC
Laakso et al. [17] 99 (12) 56 (6) 142 (6) Stepped EIC
Rizza et al. [18] - 55 (15) - Stepped EIC
Kolterman et al. [6] 221 (20) 130 (7) 270 (13) Multiple EIC

These values are compared to I50 identified with the saturable model.