Table 7: List of Genes Obtained in MLL Dataset

Index Probe Id Gene Symbol Description Marker Genes Similarity Measure Jaccard Cosine
1 37954_AT ANXA8L2 Annexin A8 ✓ ✓
2 34375_AT CD163 CD163 Antigen ✓ ✓
3 34375_AT CCL2 Chemokine (C-C Motif) Ligand 2 a ✓ ✓
4 875_G_AT CCL2 Chemokine (C-C Motif) Ligand 2 ✓ ✓
5 37187_AT CXCL2 Chemokine (C-X-C Motif) Ligand 2 a,b ✓ ✓
6 36780_AT CLU Clusterin ✓ ✓
7 40282_S_AT CFD Complement Factor D (Adipsin) a ✓ ✓
8 1914_AT CCNA1 Cyclin A1 ✓ ✓
9 39660_AT DEFB1 Defensin, Beta 1 ✓ ✓
10 864_AT MNX1 Homeobox HB9 ✓ ✓
11 37043_AT ID3 Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein ✓ ✓
12 1389_AT MME Membrane Metallo-Endopeptidase f ✓ ✓
13 38604_AT NPY Neuropeptide Y ✓ ✓
14 36151_AT PLD3 Phospholipase D Family, Member 3 ✓ ✓
15 39208_I_AT PPBP Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) ✓ ✓
16 39209_R_AT PPBP Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) ✓ ✓
17 37185_AT SERPINB2 Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 2 ✓ ✓
18 1325_AT SMAD1 SMAD, Mothers Against DPP Homolog 1 (Drosophila) ✓ ✓
19 37280_AT SMAD1 SMAD, Mothers Against DPP Homolog 1 (Drosophila) ✓ ✓
20 41097_AT TERF2 Telomeric Repeat Binding Factor 2 f ✓ ✓
21 32872_AT TCF4 PTranscription Factor 4 ✓ ✓
22 35614_AT TCFL5 Transcription Factor-LIKE 5 (Basic Helix-Loop-Helix) d,e ✓ ✓
23 1372_AT TNFAIP6 Tumor Necrosis Factor, Alpha-Induced Protein 6 c ✓ ✓

a Bloushtain-Qimron et al. 2008. Cell type-specific DNA methylation patterns in the human breast [47].
b Wagner et al. 2005. Hematopoietic Progenitor Cells and Cellular Microenvironment: Behavioral and Molecular Changes upon Interaction [53].
c S. Hanash and C. Creighton 2003. Making sense of microarray data to classify cancer [11].
d Gandemer et al. 2007. Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia [53].
e Severin et al. 2009. FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions [54].
f Armstrong et al. 2002. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia [34].