Table 3: Interaction between physical neglect and 5-HTTLPR genotypes to predict outcome variables.
|
Multiple Regression |
Mediation Analysis |
| – |
Physical neglect in childhood |
5-HTTLPR interaction |
5-HTTLPR interactiona
|
| – |
B |
95% CI |
p |
B |
95% CI |
p |
Effect |
95% CI |
p |
| Neurotic trait |
0.155 |
0.01-0.11 |
0.001 |
0.103 |
-0.02-0.37 |
0.088 |
0.002 |
-0.002-0.012 |
>0.05 |
| Anxiety symptoms |
0.281 |
0.52-1.25 |
0.001 |
0.043 |
-0.97-2.11 |
0.467 |
0.007 |
0.009-0.084 |
>0.05 |
| Perceived stress |
0.23 |
0.26-0.77 |
0.001 |
0.014 |
-0.94-1.20 |
0.809 |
0.001 |
-0.010-0.043 |
>0.05 |
|
Hazardous alcohol use (AUDIT)
|
0.05 |
-0.01-0.02 |
0.397 |
0.093 |
-0.16-1.32 |
0.128 |
0.007 |
-0.006-0.040 |
>0.05 |
| Hazardous alcohol use (ASSIST) |
0.01 |
-0.01-0.02 |
0.871 |
0.176 |
0.04-0.20 |
0.004 |
0.006 |
-0.016-0.079 |
>0.05 |
Note: a Indirect effect of physical neglect on neurotic trait, anxiety symptoms, perceived stress and hazardous alcohol use via 5-HTTLPR genotypes.