Table 2: Subgroup Analys is of Main PD Symptoms and L-Dopa Motor Side Effects According to ACE Genotypes

N (n=77, % of total )* DD(%)** DI(%)** II(%)** p-value
Initial Symptoms
Tremor dominant 34(44.2%) 9 (30.0%) 20(54.1%) 5(50.0%) 0.13
B-R dominant 43(55.8%) 21 (70.0%) 17(45.9%) 5(50.0%)
Tremor at examination 52(67.5%) 18 (60.0%) 28(75.7%) 6(60.0%) 0.34
Rigidity at examination 58(75.3%) 23 (76.7%) 27(73.0%) 8(80.0%) 0.88
Instability at examination 38(49.4%) 18 (60.0%) 14(37.8%) 6(60.0%) 0.15
Dyskinesias 15(19.5%) 7 (23.3%) 5(13.5%) 3(30.0%) 0.40
On-off phenomena 22(28.6%) 13 (43.3%) 6(16.2%) 3(30.0%) 0.06

B-R: bradykinesia rigidity; DI: deletion/insertion polymorphism; PD: Parkinson’s disease.
* Percentage (%) of all PD patients.
** Percentage of PD patients with each genotype.