Table 2: Clinical Outcomes 0-6 Months

Outcome (range) N 0 months 6 months 0-6 month difference* SRM
Mean (SD) Mean (SD) Mean (95%-CI) P-value
Average Migraine Severity, Physician (0-10) 44 7.20 (1.37) 4.07 (2.48) 3.14 (2.40-3.87) <0.001 1.30
Average Migraine Severity, Patient (0-10) 44 6.77 (1.79) 3.93 (2.44) 2.84 (2.05-3.64) <0.001 1.09
Symptom Score (0-10) 45 6.40 (1.43) 4.08 (1.90) 2.32 (1.68-2.95) <0.001 1.10
SF-36 Physical Component 44 42.70 (8.64) 46.14 (8.04) 3.44 (1.16 to 5.73) 0.004 0.46
SF-36 Mental Component 44 39.51 (12.55) 41.55 (11.76) 2.03 (-1.07 to 514) 0.194 0.20
SF-36 Scales (0-100)
Physical Function 45 82.89 (21.91) 84.28 (20.29) 1.39 (-3,25 to 6.02) 0.549 0.09
Role Physical 45 45.56 (39.27) 56.11 (38.86) 10.56 (-0.94 to 22.05) 0.071 0.28
Role Emotional 45 61.48 (43.78) 57.78 (43.46) -3.70 (-16.73 to 9.32) 0.570 0.09
Social Functioning 45 54.44 (22.16) 67.78 (24.20) 13.33 (6.47 to 20.19) 0.001 0.58
Mental Health 45 55.69 (20.00) 59.47 (18.28) 3.78 (-0.80 to 8.35) 0.103 0.25
Bodily Pain 45 41.07 (19.45) 55.89 (24.13) 14.82 (8.12 to 21.53) <0.001 0.66
Vitality 45 40.44 (18.27) 47.44 (18.51) 7.00 (2.08 to 11.92 0.006 0.43
General Health 44 54.95 (20.14) 59.09 (18.17) 4.14 (-0.70 to 8.98) 0.092 0.26
SF-36 Health Change ** 45 3.16 (1.02) 2.40 (1.18) 0.76 (0.31 to 1.21) <0.001 0.51

* Positive differences indicate improvement.
** SF-36 Health Change: range from 1 (“much better now than one year ago”) to 5 (“much worse now than one year ago”). SRM: Standardized Response Mean effect size (minimal: < 0.20, small: 0.20-0.49, medium: 0.50-0.79, large: ≥0.80).