Fig. (1) Tyr-Tub (55kDa) immunoreactivity in brain homogenate: western blot bands (left) quantified by densitometric analysis and concomitant DPV measurements (right) after acute treatment with PCPA 500mg/kg i.p. (TOP) or with αMPT 250mg/kg (BOTTOM). Results are expressed as percent of control (vehicle treated rats); n=4 each histogram, mean ± S.D. ^*p<0.05, Dunnett’s test. Note the significant decrease, (F1,12= 7,5264 p<0.05) of Tyr-Tub following PCPA versus αMPT treatment.