Differentiating Glaucomatous from Non-Glaucomatous Optic Nerve Cupping by Optical Coherence Tomography

Table 5: Topographic Measures of the Optic Nerve Head as Measured by Stratus® Optical Coherence Tomography

Variable	All subjects: mean and standard deviation		Matched by cup-to-disc area ratio		Matched by mean RNFL
Variable	Non-glaucomatous optic nerve cupping	Glaucomatous optic nerve cupping	Non-glaucomatous optic nerve cupping	Glaucomatous optic nerve cupping	Non-glaucomatous optic nerve cupping	Glaucomatous optic nerve cupping
Disc area (mm²)	2.5 ± 0.3	2.4 ± 0.4	2.4	2.2	2.5	2.44
Cup area (mm²)	1.4 ± 0.4	1.7 ± 0.6	1.5	1.5	1.4	1.8
Rim area (mm²)	1.1 ± 0.6	0.69 ± 0.3	0.9	0.78	1.1^*	0.65
Cup-to-disc area ratio	0.56 ± 0.18	0.70 ± 0.14	0.62	0.64	0.56	0.72
Cup-to-disc horizontal ratio	0.76 ± 0.16	0.85 ± 0.10	0.83	0.82	0.75	0.87
Cup-to-disc vertical ratio	0.70 ± 0.12	0.81 ± 0.08	0.76	0.78	0.71	0.82
Total	n = 11	n = 12	n = 8	n = 8	n = 11	n = 11

^* p<0.05.

all p values were Bonferroni adjusted.RNFL= retinal nerve fiber layer.