Table 2: Demographics and 8-OHdG Concentrations of Patients with Good and Poor Outcomes

Good (mRS ≤2) Poor (mRS ≥3) P value
(n=19) (n=25)
Age 70 72 0.541
Male/female 12:07 13:12 0.066
Stroke subtypes
 LAC/AT/CE (n)  6/11/2  3/11/11 0.038
Previous stroke, % (n) 21 (4) 20 (5) 1.000
Atrial fibrillation, % (n) 26 (5) 44 (11) 0.344
Risk factors for arteriosclerosis
 Hypertension, % (n) 68 (13) 60 (15) 0.753
 Diabetes mellitus, % (n) 26 (5) 20 (5) 0.723
 Hyperlipidemia, % (n) 32 (6) 44 (11) 0.535
 Number of risk factors 1.3 1.2 0.697
Baseline NIHSS 3.7 14.1 0.001
Time from onset to arrival (h) 15.8 12.3 0.177
Edaravone, % (n) 74 (14) 80 (20)
8-OHdG concentration (ng/mgCr)
 Day 0 12.1 ± 6.3 13.3 ± 11.2 0.538
 Day 7 12.8 ± 6.1 17.1 ± 14.1 0.205
Δ8-OHdG (%) 2.54 39.44 0.004

LAC; lacunar infarction, AT; atherothrombotic infarction, CE; cardioembolic infarction