Table 3: Demographics and Δ8-OHdG Concentrations of Patients Treated with or Without Edaravone

Edaravone (+) Edaravone (–) P value
(n=34) (n=10)
Age 71 71 0.094
Male/female 21/13  5/5 0.716
Stroke subtypes
 LAC/AT/CE (n) 7/16/11  2/6/2 0.719
Risk factors for arteriosclerosis
 Hypertension, % (n) 56 (19) 80 (8) 0.271
 Diabetes mellitus, % (n) 18 (6) 30 (3) 0.402
 Hyperlipidemia, % (n) 44 (15) 10 (1) 0.067
Atrial fibrillation, % (n) 33 (12) 40 (4) 1
Time from onset to arrival (h) 9.5 30.3 0.037
Baseline NIHSS (range) 11.1 (2-37) 6.1 (1-9) 0.842
NIHSS 14 days after admission (range) 6.3 (0-28) 3 (1-8) 0.644
mRS at discharge 2.5 2.7 0.597
Medications
 Antithrombotic, % (n) 44 (15) 80 (8) 0.076
 Glycerol, % (n) 86 (29) 60 (6) 0.175
Length of stay (days) 32 29.7 0.123
Δ8-OHdG (%) 20.8 21.3 0.777

LAC; lacunar infarction, AT; atherothrombotic infarction, CE; cardioembolic infarction