| Period | Name | Comments |
|---|---|---|
| 1196-1190 B.C | Egyptian monuments and mummies | Pharaoh Siptah with deformity probably due to congenital abnormality rather than to poliomyelitis |
| 5th-4th Century B.C | Hippokrates, Ploutarchos | Role of prematurity, congenital infections and prenatal stress |
| 10 B.C.- 54 A.C Suetonius (70 A.D-130 A.D.) |
Caesar Tiberius Claudius Nero Germnicus (10 B.C.- 54 A.C.) | May have also suffered from athetoid CP described “The Twelve Caesars” |
| 1812-1820
1820-1830 1830-1831 |
Reil, Cazauviehl, Lejumeau, de Kergaradec Andrey, Heine, Depeck Billard, Cruveilhier, Breschet, Lallemand, Rokitansky |
Reported “cerebral atrophy” in adult Reported cerebral atrophy in children |
| 1842-1861 | Henoch, Little, Strommeyer | Noted an association between prematurity, prolonged labor, asphyxia, neonatal convulsions and the use of obstetrical forceps with later spastic diplegia in children |
| 1889 | Osler | First two introduce the term “cerebral palsy” and provided the first classification of CP |
| 1891-1897 | Freud | Included prenatal factors in pathogenesis of CP. Provided the most comprehensive classification for spastic diplegia |
| 1885-1888 | Mc Nutt, Gower | Described “birth palsies” and identified “first born” children as being at risk for CP. |
| 1953 | Apgar | Set a score describing an infant’s condition at birth |
| 1960 | Bobath, Vojta | Need to correct abnormal postural reflexes, especially in very early life |
| 1970-1980 | Sonography, imaging | Use of brain CT/ MRI |
| 1990 | Botulinum Toxin, | Management of spasticity with Botulinum Toxin |
| 2000 | Functional MRI, PET, | Use of MRI, SPECT and PET |
| 2000-2008 | Gross Motor Function Classification System (GMFCS), Bimanual Fine Motor Function (BFMF), Manual Ability Classification System (MACS) |