| Inclusion Criteria | Exclusion Criteria | |
|---|---|---|
| Study Design | Randomized Controlled Trials | Case reports, observational studies, systematic and narrative reviews, letters, editorials, and commentaries |
| Population | Human subjects, age <12 years, confirmed diagnosis of food allergy | Non-human subjects, age >12 years, not diagnosed or treated for food allergy |
| Intervention | Extensively hydrolyzed protein formula or amino acid-based formula supplemented with probiotics and/or prebiotics | Probiotic and/or prebiotic supplementation without being added to formula |
| Outcomes | Severity and extent of atopic eczema, fecal characteristics, tolerance, inflammatory factors, anthropometric factors, incidence of infection, allergic symptoms (respiratory, dermatological, gastrointestinal) | Symptoms unrelated to food allergy |