| – | NMOSD | MS | Idiopathic | p1 value | p2 value | p3 value |
|---|---|---|---|---|---|---|
| NMOSD & MS | NMOSD & Idiopathic | MS & Idiopathic | ||||
| Number of patients | 58 | 23 | 69 | – | – | – |
| Mean age at onset ± SD (years) | 39.1+/-14.5 | 45.2+/-10.2 | 45.4+/-12.8 | 0.046 | 0.007 | 0.96 |
| Female:male (N) | 57:1 | 23:0 | 41:28 | 0.84 | <0.001 | <0.001 |
| Unilateral (N, RE/LE) | 41(24/17) | 17(12/5) | 54(27/27) | – | – | – |
| Bilateral (N, %) | 17 (29.3) | 6 (26.1) | 15 (21.7) | 0.766 | 0.333 | 0.681 |
| Ocular pain (N, %) | 11 (19.0) | 10 (43.5) | 26 (37.7) | 0.031 | 0.023 | 0.599 |
| Normal disc appearance (N, %) |
50 (86.2) | 18 (78.3) | 36 (52.2) | 0.461 | <0.001 | 0.014 |
| Abnormal disc appearance (N, %) | 8 (13.8) | 5 (21.7) | 33 (47.8) | – | – | – |
| - Edema (N, %) | 8 (13.8) | 5 (21.7) | 33 (47.8) | 0.462 | <0.001 | 0.01 |
| - Disc hemorrhage (N, %) | 0 (0) | 1 (4.3) | 12 (17.4) | 0.517 | <0.001 | 0.048 |
| Initial BCVA | – | – | – | – | – | – |
| - mean LogMAR visual acuity ± SD |
1.88+/-0.84 | 1.66+/-0.87 | 1.35+/-0.93 | 0.309 | 0.001 | 0.149 |
| - 20/20-20/60 (N, %) | 6 (10.3) | 3 (13.7) | 23 (33.3) | 0.784 | 0.001 | 0.036 |
| - 20/70-20/200 (N, %) | 9 (15.6) | 3 (13.7) | 12 (17.4) | 0.787 | 0.777 | 0.626 |
| - <20/200 (N, %) | 43 (74.1) | 17 (74.0) | 34 (49.3) | 0.985 | 0.004 | 0.032 |
| Associated autoimmune disease (N, %) | 3 (5.1) | 1 (4.3) | 2 (2.9) | 0.866 | 0.519 | 0.761 |