Table 2: Intergroup comparison of mean values of tear osmolarity, TBUT, Schirmers 1 without and with anaesthesia at one week and 3 months post-operative.
| (Mean±SD) |
Group A (Cyclosporine+ Lubricant) |
Group B (Lubricant) |
Group C (Control) |
P-Value |
| Tear Osmolarity (mOsm/lt) |
- |
- |
- |
- |
| Pre |
303.0±8.0 |
299.4±10.8 |
303.1±12.8 |
0.061 |
| 1 week |
305.8± 6.1 |
309.4± 13.2 |
310.1± 10.0 |
0.359 |
| 3 month |
299.3± 10.6 |
302.8± 13.5 |
310.1± 14.7 |
0.041 |
| TBUT (sec) |
- |
- |
- |
- |
| Pre |
6.9±2.5 |
6.5±2.3 |
5.4±2.9 |
0.064 |
| 1 week |
6.6± 2.8 |
6.4± 3.4 |
5.0± 2.6 |
0.191 |
| 3 month |
8.7± 3.5 |
6.1± 2.1 |
4.4± 2.6 |
0.00 |
| Schirmer’s 1 without anaesthesia (mm) |
- |
- |
- |
- |
| Pre |
17.4±8.6 |
18.2±8.9 |
13.4±7.5 |
0.341 |
| 1 week |
22.1± 8.4 |
18.2± 8.5 |
18.9± 10.9 |
0.380 |
| 3 month |
24.2± 9.2 |
21.7± 9.3 |
18.8± 11.3 |
0.292 |
| Schirmer’s 1 with anaesthesia (mm) |
- |
- |
- |
- |
| Pre |
15.6±8.5 |
14.2±7.6 |
16.7±8.4 |
0.620 |
| 1 week |
16.9± 6.9 |
12.6± 6.6 |
15.8± 8.9 |
0.297 |
| 3 month |
19.2± 9.0 |
15.8± 8.8 |
15.4± 10.9 |
0.371 |
TBUT= Tear film break up time, SD = Standard Deviation